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Changes to diet, physical activity, behaviour may reduce obesity in children, adolescents

Two  Cochrane Reviews  published today are the last in a series of related systematic reviews summarizing evidence on the effects of different interventions for treating obesity and overweight in childhood and adolescence. The reviews summarize the results of 114 studies which involved over 13,000 children and young people. They show that a combination of diet, physical activity and behavioural change interventions may reduce weight in children aged six to 11 years and in adolescents aged 12 to 17, but there are limitations in the studies and variation in the results. Childhood and adolescent obesity is one of the leading global public health concerns. Rapid weight gain in children as young as six years old has increased globally, and has significant mental and physical health consequences such as diabetes, high blood pressure, asthma, sleep problems and low self-esteem. Obesity in childhood and adolescence can persist into adulthood, increasing the risk of poor health i...

High fat diet reduces gut bacteria, Crohn's disease symptoms

In the new study, a diet of plant-derived "good" fats, including coconut oil or cocoa butter, drastically reduced bacterial diversity in mice with Crohn's-like disease. Mice fed beneficial fatty diets had up to thirty percent fewer kinds of gut bacteria as those fed a normal diet, collectively resulting in a very different gut microbial composition. Some of the species changes showed up in feces, while others were different in cecum, a portion of the intestine commonly inflamed in Crohn's disease. Mice fed even low concentrations of coconut oil or cocoa butter also had less severe small intestine inflammation. "The finding is remarkable because it means that a Crohn's patient could also have a beneficial effect on their gut bacteria and inflammation by only switching the type of fat in their diet," said Alexander Rodriguez-Palacios, DVM, DVSc, PhD, first author on the study and Assistant Professor of Medicine at Case Western Reserve University. ...